The Bax/Bak ortholog in Drosophila, Debcl, exerts limited control over programmed cell death
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چکیده
منابع مشابه
The Bax/Bak ortholog in Drosophila, Debcl, exerts limited control over programmed cell death.
Bcl-2 family members are pivotal regulators of programmed cell death (PCD). In mammals, pro-apoptotic Bcl-2 family members initiate early apoptotic signals by causing the release of cytochrome c from the mitochondria, a step necessary for the initiation of the caspase cascade. Worms and flies do not show a requirement for cytochrome c during apoptosis, but both model systems express pro- and an...
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Apoptosis is a genetically controlled form of cell death that is an important feature of animal development and homeostasis. The genes involved in the control and execution of apoptosis are conserved throughout evolution. However, the actual molecular mechanisms used by these genes vary from species to species. In this review, we focus on the genetic components of apoptosis in the fruit fly Dro...
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The deliberate and orderly removal of cells by programmed cell death is a common phenomenon during the development of metazoan animals. We have examined the distribution and ultrastructural appearance of cell deaths that occur during embryogenesis in Drosophila melanogaster. A large number of cells die during embryonic development in Drosophila. These cells display ultrastructural features that...
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ژورنال
عنوان ژورنال: Development
سال: 2009
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.019042